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(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride

(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine hydrochloride

CAS: 171482-05-6

Molecular Formula: C20H19ClF7NO2

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  5. (2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride - Names and Identifiers

Name (2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine hydrochloride
Synonyms Aprepitant HCl
APREPITANT INTERMEDIATES
Aprepitant M2 Metabolite (1R, 2R, 3S)
(2R, 3S)-2-(1R)-1-(3, 5-BIS (TRIFLUOROMETHYL)-3-(4-FLUOROPHENYL) MORPHOLINE HYDROCHLORIDE
(2R,3S)-2-[(1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)morpholine HCl
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydrochlor
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride
(2R, 3S)-2-(1R)-1-3,5-Bis(trifluoromethyl)phenyl)ethoxy-3-(4-fluorophenyl)morpholine, hydrochloride
(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine hydrochloride
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride
(2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE
(2R,3S)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl)Ethoxy]-3-(4-Fluorophenyl)Morpholine Hydrachloride
(2R,3S)-2-[(1R)-l-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-morpholine hydrochloride
CAS 171482-05-6
EINECS 691-262-0

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride - Physico-chemical Properties

Molecular FormulaC20H19ClF7NO2
Molar Mass473.82
Storage ConditionInert atmosphere,Room Temperature

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride - Reference Information

overview the chemical name of aprepitant (Aprepitant) is 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis (trifluoromethyl) phenyl] ethoxy]-3-(4-fluorophenyl)-4-morpholinyl] methyl]-1, 2-Dihydro-3H-1, 2, 4-triazol-3-one is an antiemetics developed by Merck in the United States to prevent acute and delayed vomiting during chemotherapy. Clinical studies have shown that when using moderate and highly emetic chemotherapy drugs, adjuvant administration of aprepitant can significantly control the symptoms of nausea and vomiting (CINV) caused by chemotherapy.
use aprepitant intermediate can be used to treat depression and chemotherapy-induced vomiting intermediate.
Last Update：2024-04-09 21:04:16
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride
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Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
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CAS: 171482-05-6
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE Visit Supplier Webpage Request for quotation
CAS: 171482-05-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Aprepitant Impurity 52 Visit Supplier Webpage Request for quotation
CAS: 171482-05-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE Visit Supplier Webpage Request for quotation
CAS: 171482-05-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
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(2R,3S)-2-((R)-1-(3,5-Bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine hydrochloride
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